No. Study ID Diagnostic criteria Number (T/C) Age, years (T/C) Interventions Outcomes Control group Treatment group Duration Adverse events 1 Lin et al. [14 ] The total number of leukocytes remained below 4.0 20/19 52.1 ± 7.65/53.7 ± 6.14 Oral medicine (leucogen tablets) Acupoint injection at ST36 with Shenmai injection 1× per day for 21 days (21 total) Not mentioned TER 2 Wang [15 ] The total number of leukocytes remained below 4.0 20/18 55.35 ± 9.73/54.80 ± 8.15 Oral medicine (blood increasing pill) Moxibustion at ST36, CV4, and CV6 1× per day for 7 days (7 total) No local scalds and no allergies or discomfort caused by other treatments during and after treatment LC, TER, and KI 3 Fan [16 ] The total number of leukocytes remained below 4.0 30/30 57.72 ± 12.09/61.59 ± 12.78 Intravenous drip of Shenqi Fuzheng injection Ginger moxibustion at GV14, BL20, BL23, BL17, CV12, CV14, and CV4 for 4 moxa cone 1× per day for 10 days (10 total) A total of 4 cases of adverse events occurred (two were intolerable to moxa smoke, one had blisters from moxibustion, and one treated middle back pruritus). LC 4 Lu et al. [17 ] WHO grading standards 30/30 30–76/40–75 Intravenous drip of granisetron hydrochloride injection Intravenous drip of granisetron hydrochloride injection + acupoint injection at ST36 with Aidi injection ND Not mentioned LC 5 Yang [18 ] The total number of leukocytes remained below 4.0 27/30 56.04 ± 10.98/54.10 ± 11.02 rhG-CSF injection rhG-CSF injection + moxibustion with warming needle at ST36, BL17, CV4, and CV6 1× per day for 7 days (7 total) No signs of infection LC and TER 6 Fu et al. [19 ] The total number of leukocytes remained below 4.0 38/38 55–79; mean: 61.5 ± 8.9 Oral medicine (leucogen tablets and batilol tablets) Moxibustion with warming needle at ST36, SP6, SP9, SP10, GV14, BL20, PC6, CV4, and CV6 1× per day for 14 days (14 total) Not mentioned TER 7 Wang et al. [20 ] WHO grading standards 37/35 54.24 ± 7.89/51.25 ± 8.97 Oral medicine (leucogen tablets and batilol tablets) Moxibustion at ST36, SP6, SP10, CV4, and CV8 for 4 moxa cone (1× per day for 14 days, rest 7 days) Not mentioned LC and TER 8 Zhang [21 ] The total number of leukocytes remained below 4.0 16/16 60.06 ± 7.54/61.38 ± 8.40 rhG-CSF injection Moxibustion with seed-sized moxa cone at ST36 and GV14 for 9 moxa cone 1× per day ND LC and TER 9 Tian [22 ] WHO grading standards 34/34 32–76; mean: 51.6 ± 4.3 Oral medicine (leucogen tablets and batilol tablets) Moxibustion at ST36, CV4 and CV6 for 15 minutes 1× per day for 14 days (14 total) Not mentioned LC 10 Hu [23 ] The total number of leukocytes remained below 4.0 30/30 1.30 ± 9.64/52.03 ± 8.87 Oral medicine (batilol tablets) or subcutaneous injection of rhG-CSF injection Oral medicine (batilol tablets) or subcutaneous injection of rhG-CSF injection + acupuncture at ST36, SP6, SP10 and BL23 for 30 minutes 1× per day for 5 days (5 total) Not mentioned LC and TER 11 Zhu [24 ] The total number of leukocytes remained below 4.0 40/38 47 ± 16/46 ± 14 Oral medicine (batilol tablets) or subcutaneous injection of rhG-CSF injection Oral medicine (batilol tablets) or subcutaneous injection of rhG-CSF injection + acupuncture at ST36, SP6, BL18, BL23, CV4, and SP10 1× per day for 5 days (5 total) ND LC and TER 12 Chen and Xu [25 ] Definitive diagnosis without basis 52/50 38–72/37–70 Oral medicine (leucogen tablets and berbamine hydrochloride tablets) Oral medicine (leucogen tablets and berbamine hydrochloride tablets) + moxibustion at ST36 for 15 minutes 1× per day for 7 days (7 total) No adverse events found LC and TER 13 Mo et al. [26 ] WHO grading standards 41/41 55 ± 10/56 ± 10 Oral medicine (leucogen tablets and batilol tablets) Moxibustion at ST36, CV4, CV6, and CV8 for 20 minutes 6× per week for 3 weeks (18 total) Not mentioned LC, TER, and KI 14 Nie [27 ] The total number of leukocytes remained below 4.0 24/24 49.09 ± 8.01/51.2 ± 6.04 rhGM-CSF Injection Moxibustion at GV14, CV4, CV8, BL17, BL20, and BL23 1× per day for 10 days (10 total) Not mentioned LC and TER 15 Wang [28 ] The total number of leukocytes remained below 4.0 36/36 57.21 ± 7.37/57.30 ± 8.37 Oral medicine (Shenqi tablets) Acupoint injection at ST36 with Shenfu injection 1× per day for 7 days (7 total) No obvious adverse events such as skin rashes and allergies during the study LC and KI 16 Gong et al. [29 ] WHO grading standards 50/50 4.17 ± 5.71/51.49 ± 6.27 Oral medicine (batilol tablets and vitamin B4 tablets) Ginger moxibustion at CV4, CV6, and CV8 1× per day for 10 days (10 total) Not mentioned LC, TER, and KI 17 Li et al. [30 ] The total number of leukocytes remained below 4.0 80/80 8.35 ± 9.27/66.70 ± 12.13 Subcutaneous injection of rhG-CSF injection Subcutaneous injection of rhG-CSF injection + moxibustion at ST36, CV4, CV6, BL23, and GV4 1× per day for 14 days (14 total) Not mentioned LC
