Virtual Screening Technique Used to Estimate the Mechanism of Adhatoda vasica Nees for the Treatment of Rheumatoid Arthritis Based on Network Pharmacology and Molecular Docking

Table 1

RA-related potential target information.

Number	UniProt name	Target	Gene	Frequency
1	Q02127	Dihydroorotate dehydrogenase (quinone), mitochondrial	DHODH	13
2	P47989	Xanthine dehydrogenase/oxidase	XDH	11
3	P35354	Prostaglandin G/H synthase 2	PTGS2	7
4	P01375	Tumor necrosis factor	TNF	7
5	P60568	Interleukin-2	IL2	7
6	P28845	Corticosteroid 11-beta-dehydrogenase isozyme 1	HSD11B1	5
7	P28482	Mitogen-activated protein kinase 1	MAPK1	5
8	O15530	3-Phosphoinositide-dependent protein kinase 1	PDPK1	4
9	P37231	Peroxisome proliferator-activated receptor gamma	PPARG	4
10	P52333	Tyrosine-protein kinase JAK3	JAK3	4
11	Q04760	Lactoylglutathione lyase	GLO1	3
12	P19793	Retinoic acid receptor RXR-alpha	RXRA	3
13	O60674	Tyrosine-protein kinase JAK2	JAK2	3
14	P05164	Myeloperoxidase	MPO	2
15	Q04828	Aldo-keto reductase family 1 member C1	AKR1C1	2
16	P30044	Peroxiredoxin-5, mitochondrial	PRDX5	2
17	P04278	Sex hormone-binding globulin	SHBG	2
18	Q03181	Peroxisome proliferator-activated receptor delta	PPARD	2
19	P42574	Caspase-3	CASP3	2
20	P33261	Cytochrome P450 2C19	CYP2C19	1
21	Q14289	Protein-tyrosine kinase 2-beta	PTK2B	1
22	P03956	Interstitial collagenase	MMP1	1
23	P09488	Glutathione S-transferase Mu 1	GSTM1	1
24	P14555	Phospholipase A2, membrane associated	PLA2G2A	1
25	P09871	Complement C1s subcomponent	C1S	1