Effect of Moxibustion on Inflammatory Cytokines in Animals with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

Table 4

Subgroup analysis for the effect of moxibustion on reducing IL-1β.

		Heterogeneity		Effect size
			I^2 (%)	95% CI
Moxibustion	SM	0.00001	90	SMD = 4.58 (2.30, 6.86)	<0.0001
	SSMC	0.00001	94	SMD = 3.60 (0.49, 6.71)	=0.02
Model	CFA	0.00001	95	SMD = 4.75 (2.19, 7.30)	= 0.0003
	CIA	0.0002	88	SMD = 3.47 (0.67, 6.27)	=0.02
Species	SD	0.00001	91	SMD = 3.25 (1.47, 5.04)	=0.0004
	Wister	0.0003	92	SMD = 6.87 (−0.29, 14.02)	=0.06
Weight	160–200 g	0.00001	96	SMD = 4.17 (0.72, 7.62)	=0.02
	180–220 g	0.00001	90	SMD = 5.71 (2.49, 8.94)	<0.00001
Gender	Male	0.00001	87	SMD = 3.89 (2.14, 5.65)	<0.0001
	Male/female	0.00001	96	SMD = 5.36 (−4.87, 15.60)	=0.3
Publication	Yes	0.00001	94	SMD = 4.61 (2.58, 6.64)	<0.00001
	No			SMD = 2.02 (0.75, 3.29)	=0.002