Research Article

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Compound Glycyrrhizin Capsules Combined with a Topical Corticosteroid in Adults with Chronic Eczema

Table 4

Summary of subjects experiencing adverse events.

Clinical centerSubject numberAdverse eventDiscontinued trialSeverityCorrelationInduced by test drug

OCG+TCS group
H132Edema of both lower limbsNoModeratePossibleYes
H134HypokalemiaNoMildPositiveYes
H135Edema of both lower limbsYesMildPossibleYes
H2210Persistent blood pressure elevationNoMildPossibleNo
H7125Trunk and limb skin itchYesMildPossibleYes
H2184Edema of both lower limbsNoMildPossibleYes
H2190Blood pressure elevationNoMildPossibleYes
H2202Renal contusionNoMildNegativeNo

Placebo+TCS group
H2203Transaminase elevationNoMildNegativeNo
H495Urine occult bloodNoMildPossibleNo
H3164Facial edemaNoMildPossibleYes