Berberine Suppressed Tumor Growth through Regulating Fatty Acid Metabolism and Triggering Cell Apoptosis via Targeting FABPs

Figure 2

Berberine induced apoptosis of MGC803 cells. (a) Berberine treatment at 10, 20, and 40 μm for 24 h promoted the apoptosis of MGC803 cells, as detected by flow cytometry and statistically analyzed in (b). (c) Berberine treatment at 10, 20, and 40 μm for 24 h downregulated the protein expression of antiapoptosis protein Bcl-2 and promoted the protein expression of proapoptosis protein Bax and activated the expression of caspase3 protein. (d) The protein expression of apoptosis-related proteins of MGC803 cells after berberine treatment was quantified. , , , and vs controls.

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