Research Article

Cucurbitacin D Induces G2/M Phase Arrest and Apoptosis via the ROS/p38 Pathway in Capan-1 Pancreatic Cancer Cell Line

Figure 1

Cytotoxic effect of cucurbitacin D (CuD) on Capan-1 cell line: (a) chemical structure of CuD, (b) cell viability of pancreatic cancer cell lines upon exposure to CuD using the MTT assay. , , and , significantly different as compared to the control, and (c) effect of CuD on Capan-1 and AsPC-1 cell morphology (bright-field image, 100x magnification).