Pharmacological Activity of Eriodictyol: The Major Natural Polyphenolic Flavanone

Figure 2

Effect of ER on the cell cycle arrest at G2/M phase, and avoidance of apoptosis. Eriodictyol easily penetrates into the cell via cell receptors and modulates multiple signaling cascades especially PI3K/mTOR that stops the G2-Phase, and hence helps the cells avoid apoptosis.