Research Article

In Vivo Antimalarial Evaluation of Crude Extract, Solvent Fractions, and TLC-Isolated Compounds from Olea europaea Linn subsp. cuspidata (Oleaceae)

Table 3

Effect of the crude extract of O. europaea on parasitaemia of P. berghei infected mice.

TreatmentDose (mg/kg)Antimalarial activities
% parasitaemia ± SEM% suppression

Crude extract20021.06 ± 0.6430.24a3
40017.32 ± 1.9642.63a3
60014.37 ± 0.7752.40a3b1
Dist. water10 ml/kg30.19 ± 1.850.00
Chloroquine250.00100.00abcd3

Values are expressed as mean ± SEM; n = 6; a = compared to negative control; b = compared to 200 mg/kg; c = compared to 400 mg/kg; d = compared to 600 m/kg; ; .