Research Article

In Vivo Antimalarial Evaluation of Crude Extract, Solvent Fractions, and TLC-Isolated Compounds from Olea europaea Linn subsp. cuspidata (Oleaceae)

Table 7

Effect of compounds C and D on parasitaemia of P. berghei infected mice.

TreatmentDose (mg/kg)Antimalarial activities
% parasitaemia ± SEM% suppression

Compound C10032.44 ± 0.8324.82a3
20026.67 ± 0.6938.19a3b2
Compound D10036.77 ± 0.5114.79
20034.49 ± 2.0320.07a2
Dist. water10 ml/kg43.15 ± 1.490.00
Chloroquine250.00100AD3

Values are expressed as mean ± SEM; n = 6; a = compared to negative control; b = compared to 100 mg/kg of compound C; AD = compared to all doses; ; .