Anti-Inflammatory Effects of Fermented Bark of Acanthopanax sessiliflorus and Its Isolated Compounds on Lipopolysaccharide-Treated RAW 264.7 Macrophage Cells

Table 3

IC₅₀ values for inhibition of NO production by AS, FAS, and isolated compounds 1–10.

Extract	IC50 (μg/mL)	Compound	IC50 (μM)
AS	26.56 ± 1.28^b	1	57.71 ± 2.33^c
FAS	12.37 ± 0.92^a	2	>100^e
L-NMMA	10.16 ± 0.85^a	3	>100^d
		4	40.63 ± 3. 38^b,c
		5	45.80 ± 8.28^b,c
		6	>100^d
		7	26.16 ± 1. 37^a,b
		8	37.35 ± 7.97^b,c
		9	7.95 ± 2.03^a
		10	21.87 ± 1.02^a,b
		L-NMMA	19.68 ± 5.38^a,b

Values are expressed as the mean ± SD of triplicate experiments. Values with different superscripts (a–e) in the same columns are significantly different ().