Hepatoprotective Effect of Pericarpium zanthoxyli Extract Is Mediated via Antagonism of Oxidative Stress

Table 2

General histomorphometrical analysis of acute CCl₄-treated mouse hepatic tissues.

Groups	General histomorphometry
	Histological activity index (scores; max = 10)	Percentages of degenerative regions (%/mm^2)	Numbers of degenerative hepatocytes (cells/1000 hepatocytes)	Numbers of inflammatory cells infiltrated (cells/mm^2)
Control	0.40 ± 0.55	1.54 ± 0.78	14.80 ± 7.95	24.20 ± 6.98
PZE 300	0.40 ± 0.55	1.53 ± 0.87	15.00 ± 7.78	23.80 ± 12.64
CCl4	8.20 ± 1.10^a	83.37 ± 6.10^c	808.80 ± 78.10^c	223.00 ± 76.42^c
CCl4 + silymarin	4.40 ± 0.55^ab	47.02 ± 4.58^ce	453.20 ± 50.01^ce	71.60 ± 10.29^ce
CCl4 + PZE 100	4.60 ± 0.89^ab	48.11 ± 7.95^ce	473.60 ± 86.38^ce	71.00 ± 14.09^ce
CCl4 + PZE 300	3.40 ± 0.55^ab	38.55 ± 6.63^ce	363.80 ± 59.82^ce	51.00 ± 15.22^de

^a as compared with control by LSD test, ^b as compared with CCl₄ by LSD test, ^c and ^d as compared with control by MW test, ^e as compared with CCl₄ by MW test.