Research Article

Inhibitory Activity of Boesenbergia rotunda (L.) Mansf. Rhizome towards the Expression of Akt and NF-KappaB p65 in Acetic Acid-Induced Wistar Rats

Figure 9

Proposed anti-inflammatory mechanism of BREE in acetic acid-induced Wistar rats. Lower doses of BREE (250 mg/kg BW and 500 mg/kg BW) inhibit the activation of Akt thus resulting in the decrease of NF-kappaB p65 in the nucleus.