Antipruritic Effect of Ethyl Acetate Extract from Fructus cnidii in Mice with 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis

Figure 6

Effect of EAEFC treatment on the DNFB-induced increase in epidermal thickness of C57BL/6 mice. (a) H&E-stained skin on day 22. The dotted line indicates the epidermis and hypertrophy in the (A) control group, (B) DNFB-treated group, (C) EAEFC50 group, (D) EAEFC200 group, and (E) tacrolimus-treated group. (b) Data are presented as the mean ± SEM (N = 4). : Significant difference between the EAEFC50 and DNFB-treated groups and between the EAEFC200 and DNFB-treated groups at . n s.: No significant difference between the EAEFC200 and tacrolimus-treated groups.

(a)

(b)