Research Article

The Effect of Long-Term Traditional Chinese Medicine Treatment on Survival Time of Colorectal Cancer Based on propensity Score Matching: A Retrospective Cohort Study

Table 1

Baseline characteristics and clinical features of TCM group and the control group before and after PSM.

GroupBefore PSMAfter PSM
TCM n = 285Control n = 244 valueTCM n = 175Control n = 175 value

Gender
 Male170 (59.6)147 (60.2)0.889106 (60.6)102 (58.3)0.663
 Female115 (40.4)97 (39.8)69 (39.4)73 (41.7)
Pathology
 None16 (5.6)9 (3.7)0.24711 (6.3)8 (4.6)0.510
 Adenocarcinoma259 (90.9)226 (92.6)160 (91.4)159 (90.9)
 Squamous cell Ca1 (0.4)4 (1.6)1 (0.6)4 (2.3)
 Others9 (3.2)5 (2.0)3 (1.7)4 (2.3)
Stage
 I17 (6.0)24 (9.8)<0.00114 (8.0)10 (5.7)0.538
 II58 (20.4)93 (38.1)44 (25.1)57 (32.6)
 III90 (31.6)71 (29.1)66 (37.7)60 (34.3)
 IV120 (42.1)56 (23.0)51 (29.1)48 (27.4)
Histodifferentiation
 Unknown40 (14.0)18 (7.4)0.00521 (12.0)16 (9.1)0.460
 Low14 (4.9)8 (3.3)3 (1.7)8 (4.6)
 Moderate179 (62.8)151 (61.9)110 (62.9)97 (55.4)
 Moderate-low16 (5.6)47 (19.3)11 (6.3)35 (20.0)
 Moderate-high36 (12.6)20 (8.2)30 (17.1)19 (10.9)
Location
 Rectum115 (40.4)45 (18.4)<0.00143 (24.6)43 (24.6)1
 Colon170 (59.6)199 (81.6)132 (75.4)132 (75.4)
Surgery
 Yes258 (90.5)224 (91.8)0.607158 (90.3)160 (91.4)0.711
 No27 (9.5)20 (8.2)17 (9.7)15 (8.6)
Chemotherapy
 Yes221 (77.5)198 (81.1)0.309143 (81.7)145 (82.9)0.779
 No64 (22.5)46 (18.9)32 (18.3)30 (17.1)
Hypertension
 Yes79 (27.7)81 (33.2)0.17253 (30.3)50 (28.6)0.725
 No206 (72.3)163 (66.8)122 (69.7)125 (71.4)
Diabetes
 Yes75 (26.3)65 (26.6)0.93347 (26.9)32 (18.3)0.055
 No210 (73.7)179 (73.4)128 (73.1)143 (81.7)
Smoking
 Yes122 (42.8)60 (24.6)<0.00156 (32.0)54 (30.9)0.818
 No163 (57.2)184 (75.4)119 (68.0)121 (69.1)
Drinking
 Yes68 (23.9)55 (22.5)0.72035 (20.0)36 (20.6)0.894
 No217 (76.1)189 (77.5)140 (80.0)139 (79.4)
Intestinal obstruction
 Yes33 (11.6)45 (18.4)0.02623 (13.1)31 (17.7)0.236
 No252 (88.4)199 (81.6)152 (86.9)144 (82.3)
Family history
 Yes89 (31.2)58 (23.8)0.05650 (28.6)47 (26.9)0.720
 No196 (68.8)186 (76.2)125 (71.4)128 (73.1)
Age
 >60220 (77.2)204 (83.6)0.065146 (83.4)140 (80.0)0.407
 ≤6065 (22.8)40 (16.4)29 (16.6)35 (20.0)

PSM: propensity scores matching; , there was a significant statistical difference in the subgroup.