Low risk, a in two of the studies [45, 50] significant results were evaluated
E3
Erroneous assessment of risk of bias of “other sources of bias”
“at least 16 studies”
Other source of bias
Unclear risk
Low risk, as “bad reporting quality” is not a defined criterion for assessing the risk of bias according to the Cochrane Handbook
E4
Erroneous assessment of risk of bias of “other sources of bias”
Other source of bias
High risk
Low risk, as a “multiple testing problem” is not attributable to this study as the only primary endpoint “overall survival” has been proven in a confirmatory test
E5
Erroneous assessment of risk of bias of “other sources of bias”