Mechanisms and Molecular Targets of the Tao-Hong-Si-Wu-Tang Formula for Treatment of Osteonecrosis of Femoral Head: A Network Pharmacology Study

Table 3

Topological parameters of candidate compounds for THSWT against ONFH.

TCMSP ID	Chemical compound	Degree	Betweenness	Closeness
MOL000422	Kaempferol	15	1080.90	36.32
MOL000006	Luteolin	14	1370.81	36.17
MOL002714	Baicalein	8	394.46	31.65
MOL000358	Gibberellin 7	7	503.66	30.98
MOL002773	Beta-carotene	7	365.76	30.98
MOL000449	Stigmasterol	4	120.36	28.98
MOL000296	Hederagenin	3	66.29	28.32
MOL002135	Myricanone	3	65.72	28.32
MOL000492	(+)-catechin	3	49.35	28.32
MOL001924	Paeoniflorin	3	258.00	19.03
MOL002157	Wallichilide	2	130.00	27.65
MOL001323	Sitosterol alpha1	2	38.77	27.65
MOL001352	GA54	2	11.67	27.65
MOL001368	3-O-p-coumaroylquinic acid	2	11.67	27.65
MOL002695	Lignan	2	11.67	27.65
MOL001328	2,3-didehydro GA70	2	9.63	27.65
MOL002712	6-hydroxykaempferol	2	9.63	27.65
MOL002721	Quercetagetin	2	9.63	27.65
MOL001329	2,3-didehydro GA77	1	0.00	26.98
MOL001340	GA120	1	0.00	26.98
MOL001355	GA63	1	0.00	26.98
MOL001358	Gibberellin 7	1	0.00	26.98
MOL001361	GA87	1	0.00	26.98
MOL000493	Campesterol	1	0.00	26.98
MOL001494	Mandenol	1	0.00	26.98
MOL002140	Perlolyrine	1	0.00	26.98
MOL002694	4-[(E)-4-(3,5-dimethoxy-4-oxo-1-cyclohexa-2,5-dienylidene) but-2-enylidene]-2,6-dimethoxycyclohexa-2,5-dien-1-one	1	0.00	26.98
MOL002710	Pyrethrin II	1	0.00	26.98
MOL002717	qt_carthamone	1	0.00	26.98
MOL002757	7,8-dimethyl-1H-pyrimido[5,6-g]quinoxaline-2,4-dione	1	0.00	26.98