Research Article

Effect of Moxibustion on the Serum Levels of MMP-1, MMP-3, and VEGF in Patients with Rheumatoid Arthritis

Table 3

Changes of contents of IL-1β, TNF-α, MMP-1, MMP-3, and VEGF.

Outcome measuresTreatment group (n = 34)Control group (n = 32) value

IL-1β (pg/mL)
 Baseline30.75 (16.31)33.52 (16.34)0.493
 Posttherapy21.75 (10.61)28.56 (15.69)0.042

TNF-α (pg/mL)
 Baseline27.66 (14.12)20.60 (12.09)0.204
 Posttherapy32.43 (16.01)27.07 (13.41)0.043

MMP-1 (pg/mL)
 Baseline2.85 (1.68)3.69 (2.11)0.076
 Posttherapy2.38 (1.36)3.39 (1.72)0.010

MMP-3 (pg/mL)
 Baseline141.40 (77.16)160.11 (61.98)0.283
 Posttherapy120.77 (64.52)152.18 (58.00)0.042

VEGF (pg/mL)
 Baseline87.43 (47.65)109.84 (55.74)0.083
 Posttherapy66.27 (33.46)91.18 (47.49)0.016

Values are represented as mean (SD). value by independent samples t test.