Research Article

Oral and Topical Centella asiatica in Type 2 Diabetes Mellitus Patients with Dry Skin: A Three-Arm Prospective Randomized Double-Blind Controlled Trial

Table 4

Comparisons of CML, IL-1α, and SOD analysis in the partially controlled blood glucose subgroup.

ParameterCAo + CAtPlo + CAtPlo + Plt value

D 1
n13914
  CML (pg/mg protein)0.55
   Median (min–max)73.9 (26.7–219.9)153 (35.5–179.6)70.9 (27.5–279.4)
  IL-1α (pg/mg protein)0.67
   Median (min–max)17.3 (7–32)17.9 (4.4–96.2)16.7 (6.8–47.1)
  SOD (U/mg protein)0.28
   Median (min–max)3.9 (0.3–11.2)6 (0.4–25.3)2.7 (0.2–16.4)
D 29
n13714
  CML (pg/mg protein)0.42
   Median (min–max)158 (26–524.6)82.7 (44.3–270.1)91.8 (22–422.1)
  IL-1α (pg/mg protein)0.51
   Median (min–max)21.6 (7.9–65.9)17 (6.2–32.2)14.5 (4.9–80)
  SOD (U/mg protein)0.03
   Median (min–max)8.4 (1.3–25)a2.4 (1.3–10.5)3.5 (0.2–8.1)

Kruskal–Wallis test amongst the three groups, followed by the Mann–Whitney test, to assess the difference between each group. aCompared to Plo + Plt with .