Research Article
Proliferation of Vascular Smooth Muscle Cells under ox-LDL Is Regulated by Alismatis rhizoma Decoction via InhibitingERK1/2 and miR-17∼92a Cluster Activation
Figure 5
AD and the ERK 1/2 blocker inhibit the expression of MMP-2 and MMP-9 in ox-LDL-induced VSMCs. Western blot analysis and qPCR assay were performed to determine the expression of MMP-2 and MMP-9, while β-actin and GAPDH serves as a loading control. The graphs represent the relative expression of these proteins and mRNAs for three independent experiments. ox-LDL vs. control group; AD or U0126 vs. ox-LDL group; AD or U0126 vs. ox-LDL group.
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