An Anti-Inflammatory Composition of Boswellia serrata Resin Extracts Alleviates Pain and Protects Cartilage in Monoiodoacetate-Induced Osteoarthritis in Rats

Figure 5

LI13019F1 protects cartilage from the damaging action of MIA in Sprague-Dawley rats. Representative photomicrographs show Safranin-O green stained articular cartilage tissue sections of the LI13019F1-supplemented rats, as indicated. The panels (a), (b), (c), (d), and (e) represent the experimental groups as described in the materials and methods, i.e., normal saline, MIA-induced in the absence or presence of 75, 150, and 300 mg/kg LI13019F1 rats, respectively. The arrowheads show the presence of extracellular matrix components (red stain) and cellular structures (chondrocytes) in the articular surface of the joints. The scale bar measures 100 μm.

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