Antioxidant Effect of Standardized Extract of Propolis (EPP-AF®) in Healthy Volunteers: A “Before and After” Clinical Study

Table 1

Biochemical safety profile before (baseline) and 30 days after the end of EPP-AF® (750 mg/d). Values are expressed as mean ± SD.

	Baseline	After EPP-AF®	-value
Hemoglobin (g/dL)	13.6 ± 1.6	13.5 ± 1.4	0.99
Hematocrit (%)	40.5 ± 4.4	40.5 ± 4.0	0.41
Creatinine (mg/dL)	0.89 ± 0.14	0.87 ± 0.14	0.06
Urea (mg/dL)	26.4 ± 7.4	27.5 ± 6.8	0.28
Direct bilirrubin (mg/dL)	0.16 ± 0.06	0.17 ± 0.07	0.06
Aspartate aminotransferase (AST, U/L)	17.4 ± 3.8	17.6 ± 3.8	0.82
Alcaline phosphatase (U/L)	142.7 ± 45.8	148.7 ± 49.0	0.08
Gamma glutamyl-transferase (U/L)	24 ± 14	25 ± 13.6	0.20
Glycemia (mg/dL)	80.6 ± 6.4	79.4 ± 7.4	0.32