Combination of Red Clover and Hops Extract Improved Menopause Symptoms in an Ovariectomized Rat Model

Table 1

Biometric changes after 12 weeks of RHEC administration to OVX rats.

Group	Sham	OVX	RHEC (125)	RHEC (250)	RHEC (500)
Body weight gain (g)	80.74 ± 28.43^c	169.50 ± 32.26	138.30 ± 12.9^a	130.31 ± 20.76^a	126.53 ± 17.56^a
Visceral fat (g)	3.42 ± 1.82^c	7.84 ± 1.40	5.73 ± 1.53	5.21 ± 1.41^a	4.74 ± 0.74^b
Retroperitoneal fat (g)	3.23 ± 1.39^c	8.16 ± 2.17	6.29 ± 1.88	5.78 ± 0.82^a	5.27 ± 0.58^c
Liver (g)	6.75 ± 0.87	7.69 ± 0.66	6.75 ± 0.37	6.96 ± 0.73	6.67 ± 0.67
Kidney (g)	1.64 ± 0.14	1.68 ± 0.09	1.64 ± 0.19	1.60 ± 0.07	1.58 ± 0.19
Uterus (g)	0.54 ± 0.06^a	0.11 ± 0.02	0.09 ± 0.01	0.11 ± 0.02	0.11 ± 0.01
Uteric epithelial height (µm)	27.71 ± 5.36^a	14.34 ± 2.78	15.12 ± 1.97	14.30 ± 2.63	14.97 ± 2.59
Feed intake (g/day)	16.47 ± 1.07^c	19.98 ± 1.17	18.23 ± 0.89^a	18.61 ± 0.75	18.38 ± 1.25

Values are expressed as mean ± SD (n = 7). OVX, ovariectomy; RHEC, combination of red clover extract and hops extract; FER, food efficiency ratio. ^a versus OVX; ^b versus OVX; ^c versus OVX.