Combination of Red Clover and Hops Extract Improved Menopause Symptoms in an Ovariectomized Rat Model

Table 2

Results of serum analysis after 12 weeks of RHEC administration to OVX rats.

Group	Sham	OVX	OVX
			RHEC (125)	RHEC (250)	RHEC (500)
ALT (U/L)	35.8 ± 10.6	37.0 ± 2.5	38.8 ± 5.9	36.9 ± 4.1	35.3 ± 2.9
AST (U/L)	72.5 ± 17.1	78.0 ± 5.6	85.9 ± 8.3	79.0 ± 8.3	72.9 ± 4.9
T-Chol (mg/dL)	76.0 ± 14.7^c	123.7 ± 17.6	117.1 ± 14.1	109.6 ± 9.0	93.6 ± 10.4^c
TG (mg/dL)	69.1 ± 16.4	100.4 ± 38.7	78.0 ± 23.8	73.1 ± 10.2	65.7 ± 14.5
HDL-C (mg/dL)	58.5 ± 10.6^a	73.0 ± 6.1	81.2 ± 8.8	79.4 ± 6.3	67.7 ± 7.4
LDL-C (mg/dL)	6.8 ± 109^c	13.0 ± 1.8	15.2 ± 2.4	13.6 ± 1.2	11.4 ± 1.1
ALP (U/L)	41.1 ± 10.6^c	69.7 ± 9.8	74.0 ± 17.6	58.1 ± 11.2	52.9 ± 5.1
Osteocalcin (pg/ml)	771.4 ± 322.9^b	1723.3 ± 153.6	1743.3 ± 425.5	1498.1 ± 267.8	1265.1 ± 127.9
CTX-1 (pg/ml)	7.15 ± 1.64^c	15.40 ± 3.90	11.81 ± 2.63^a	11.53 ± 1.30^b	6.48 ± 2.02^c
SOD (U/ml)	42.625 ± 12.856^a	17.423 ± 14.266	37.263 ± 22.755	46.711 ± 11.368^a	48.704 ± 14.952^b
MDA (µM/ml)	10.24 ± 3.45^b	19.22 ± 3.86	14.65 ± 5.19	13.74 ± 3.50	11.54 ± 4.61^a

Values are expressed as mean ± SD (n = 7). OVX, ovariectomy; RHEC, combination of red clover extract and hops extract. ^a versus OVX; ^b versus OVX; ^c versus OVX.