The Protective Effects and Potential Mechanisms of Ligusticum chuanxiong: Focus on Anti-Inflammatory, Antioxidant, and Antiapoptotic Activities

Table 2

Diseases ameliorated by LC.

Disease	Drug	Dosage (mg/kg)	Model	Ref
Atherosclerosis	Total lactone	30, 60	ApoE^-/- mice	[56]
Cerebral trauma	Ligustrazine	20	Controlled cortical impact mice	[49]
Migraine	Senkyunolide I	16, 32	Nitroglycerin-treated rats	[58]
Diabetic nephropathy	Ethanol extraction	25, 50, 100	Streptozotocin-treated mice	[24]
Intervertebral disc degeneration	Ligustilide	10	Mice treated by surgery	[42]
Oxidative damage on renal	Ligustrazine	80	Gentamicin-treated mice	[59]
Ischemic cerebral stroke	Senkyunolide I	36, 72	Ischemia-reperfusion injured rats	[53]
Cognitive impairment	Ligustilide	—	D-galactose-treated mice	[60]