Supplementation of L-Arginine, L-Glutamine, Vitamin C, Vitamin E, Folic Acid, and Green Tea Extract Enhances Serum Nitric Oxide Content and Antifatigue Activity in Mice

Table 1

Biochemical analysis of mice subjected to LVFG supplementation at the end of the study.

Parameter	Vehicle	LVFG -2X	LVFG-5X	LVFG-1X	Trend analysis
AST (U/L)	85 ± 6	85 ± 8	90 ± 6	75 ± 3	0.3792
ALT (U/L)	53 ± 5	54 ± 5	46 ± 4	47 ± 3	0.3529
BUN (mg/dL)	24.4 ± 0.5	25.3 ± 1.3	27.4 ± 0.8	31.7 ± 0.9	<0.0001
Creatinine (mg/dL)	0.32 ± 0.02	0.35 ± 0.02	0.31 ± 0.01	0.32 ± 0.01	0.4556
UA (mg/dL)	1.41 ± 0.09	0.84 ± 0.07	0.78 ± 0.04	0.73 ± 0.03	<0.0001
TC (mg/dL)	162 ± 5^b	143 ± 4^a	162 ± 4^b	174 ± 4^bc	0.0287
TG (mg/dL)	179 ± 6^b	168 ± 9^b	162 ± 6^b	140 ± 6^a	<0.0001
TP (g/dL)	5.5 ± 0.2^a	6.3 ± 0.1^b	6.3 ± 0.1^b	6.2 ± 0.1^b	0.0372
Albumin (g/dL)	3.6 ± 0.1	3.6 ± 0.0	3.6 ± 0.0	3.6 ± 0.0	0.4637
Glucose (mg/dL)	148 ± 4	150 ± 4	153 ± 3	148 ± 7	0.9310

Values are mean ± SEM for n = 8 mice per group. Values in the same line with different superscripts letters (a, b, c) differ significantly () by one-way ANOVA. AST, aspartate aminotransferase; ALT, alanine aminotransferase; BUN, blood urea nitrogen; UA, uric acid; TC, total cholesterol; TG, triacylglycerol; TP, total protein.