Antiliver Fibrosis Screening of Active Ingredients from Apium graveolens L. Seeds via GC-TOF-MS and UHPLC-MS/MS

Table 1

Effects of TGF-β1 on the viability of HSC-LX2 cells (mean ± SD, n = 3).

Group	Dose (ng·mL^−1)	24 h		48 h		72 h
		OD	Viability (%)	OD	Viability (%)	OD	Viability (%)
Solvent control	—	0.183 ± 0.004	—	0.175 ± 0.004	—	0.210 ± 0.001	—
Blank control	—	0.395 ± 0.102	—	0.671 ± 0.023	—	1.739 ± 0.197	—
TGF-β1	5	0.347 ± 0.054	77.35 ± 0.75	0.711 ± 0.072	108.11 ± 3.26	0.573 ± 0.109^#	23.76 ± 2.65
	10	0.501 ± 0.028	150.72 ± 0.62	0.775 ± 0.042	121.10 ± 2.61	0.596 ± 0.035^#	25.24 ± 2.41
	20	0.511 ± 0.067	154.71 ± 0.86	0.820 ± 0.103	130.12 ± 4.51	1.316 ± 0.136	47.63 ± 1.04
	40	0.695 ± 0.105^#	215.52 ± 1.96	0.894 ± 0.110	145.21 ± 5.62	1.311 ± 0.185	72.13 ± 3.65
	80	0.640 ± 0.108^#	241.49 ± 0.21	1.093 ± 0.079^#	177.59 ± 2.54	2.472 ± 0.145^#	148.51 ± 2.54
	100	0.803 ± 0.101^#	292.45 ± 0.26	1.755 ± 0.081^##	318.39 ± 6.26	2.728 ± 0.177^#	164.54 ± 3.22

Compared with the blank control group (, ).