Research Article
Antiliver Fibrosis Screening of Active Ingredients from Apium graveolens L. Seeds via GC-TOF-MS and UHPLC-MS/MS
Table 4
Effects of PP, PE, PB, and PW on liver fibrosis indexes (mean ± SD, n = 3).
| Group | Dose (μg·mL−1) | LN (μg·L−1) | HA (ng·L−1) | PCIII (μg·L−1) |
| Blank control | 0 | 51.8 ± 0.78 | 26.9 ± 5.67 | 18.8 ± 4.53 | BJRG | 50 | 211.0 ± 5.08 | 64.5 ± 3.19 | 29.2 ± 2.53 | Model group (TGF-β1) | 0.1 | 833.4 ± 9.94## | 302.3 ± 7.44## | 115.3 ± 3.38## | PW | 75 | 638.27 ± 7.22 | 178.82 ± 3.94 | 108.87 ± 9.29##ΔΔ | PB | 75 | 502.56 ± 5.85 | 111.37 ± 4.95 | 78.36 ± 5.22#Δ | PE | 75 | 118.40 ± 5.74 | 70.80 ± 7.07 | 28.30 ± 0.21 | PP | 75 | 97.32 ± 6.30 | 30.91 ± 5.22 | 19.01 ± 4.26 |
|
|
Compared with the blank control group ( , ); compared with the model group ( , ); compared with the PP group, ( , ). |