Keratinocyte Growth Factor-2 Reduces Inflammatory Response to Acute Lung Injury Induced by Oleic Acid in Rats by Regulating Key Proteins of the Wnt/β-Catenin Signaling Pathway

Table 3

Correlation analysis between inflammatory reaction in ALI induced by oleic acid and expression of key proteins in Wnt/β-catenin signaling pathway.

Index		ALI group						ALI + KGF-2 group
		Wnt5a		β-Catenin		APC		Wnt5a		β-Catenin		APC
		r		r		r		r		r		r
Inflammatory factor	TNF-α	0.776	0.001	0.857	0.002	0.954	0.001	0.273	0.446	0.851	0.002	0.747	0.013
	IL-10	−0.879	0.001	−0.830	0.03	−0.697	0.025	−0673	0.033	−0.748	0.013	−0.852	0.002
Number of cells in BALF	White blood cell count	0.888	0.001	0.827	0.003	0.063	0.037	0.298	0.403	0.957	0.001	0.907	0.001
	Red blood cell count	0.794	0.006	0.721	0.019	0.879	0.001	0.588	0.074	0.875	0.001	0.772	0.009

Note. TNF-α is tumor necrosis factor-α. IL-10 is interleukin-10. Wnt5a, β-catenin, and APC are key proteins in the Wnt/β-catenin signaling pathway. BALF is bronchoalveolar lavage fluid.