Protective Effect of a Mixture of Astragalus membranaceus and Lithospermum erythrorhizon Extract against Hepatic Steatosis in High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mice

Figure 1

Effects of ALM16 and individual extracts (AM and LE) on hepatic steatosis in the liver of HFD-fed mice. (a) Body weight and (b) Liver weight (n = 6). (c) Representative macroscopic images of the liver. (d) Representative histopathological images of the liver tissue, stained with hematoxylin and eosin (H&E), of HFD-fed mice (magnification, 200x). Data are presented as mean ± standard error of the mean (SEM). ^#, ^##, and ^### vs ND group; , , and vs HFD group. ND: normal diet; HFD: high fat diet; AM: HFD + AM extract (100 mg/kg); LE: HFD + LE extract (100 mg/kg); ALM16-L: HFD + ALM16 (50 mg/kg); ALM16-M: HFD + ALM16 (100 mg/kg); ALM16-H: HFD + ALM16 (200 mg/kg); MT: HFD + milk thistle extract (100 mg/kg).

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