The Effect of Prophylactic Anticoagulation with Heparin on the Brain Cells of Sprague-Dawley Rats in a Cardiopulmonary-Cerebral Resuscitation Model
Table 1
Comparison of the baseline parameters and weights among different groups (mean ± SD).
Sham (n = 10)
Nonanticoagulation (n = 25)
Heparin (n = 25)
Mean arterial blood pressure (MABP, mmHg)
90 ± 6
89 ± 7
88 ± 8
Heart rate (HR, beats/min)
321 ± 21
319 ± 26
322 ± 24
End-tidal carbon dioxide (PEtCO2, mmHg)
36 ± 4
36 ± 5
35 ± 5
Fraction of inspired oxygen (FiO, %)
79 ± 3
80 ± 3
80 ± 3
Rectal temperature (RT)
37.9 ± 0.4
38.1 ± 0.6
37.9 ± 0.5
Baseline weight (g)
390 ± 28
387 ± 29
394 ± 27
Weight after 72 h
391 ± 26
343 ± 22
344 ± 1 9
Note: after 72 h, there was significant difference in the weight of in the nonanticoagulation and heparin groups compared with the weight before the experiment, .