The Effect of Prophylactic Anticoagulation with Heparin on the Brain Cells of Sprague-Dawley Rats in a Cardiopulmonary-Cerebral Resuscitation Model
Table 2
Changes in the vitals and other parameters during CPR in nonanticoagulation and heparin groups (mean ± SD).
Before asphyxiation
ROSC
10 min after ROSC
30 min after ROSC
60 min after ROSC
After ventilation
III (n = 10)
MABP (mmHg)
89 ± 7
125 ± 13
96 ± 4
87 ± 6
77 ± 7
77 ± 8
HR (bpm)
325 ± 23
419 ± 45
349 ± 10
322 ± 24
314 ± 27
286 ± 18
PEtCO2 (mmHg)
36 ± 5
44 ± 4
37 ± 4
33 ± 2
36 ± 3
35 ± 3
RT (°C)
38.1 ± 0.6
37.5 ± 0.4
37.7 ± 0.4
37.9 ± 0.2
38.2 ± 0.4
38.4 ± 0.3
IV (n = 21)
MABP (mmHg)
88 ± 8
145 ± 10
98 ± 5
99 ± 7
86 ± 6
79 ± 9
HR (bpm)
322 ± 19
409 ± 39
358 ± 11
318 ± 21
317 ± 25
289 ± 17
PEtCO2 (mmHg)
35 ± 5
41 ± 5
37 ± 4
34 ± 2
35 ± 2
35 ± 3
RT (°C)
37.9 ± 0.5
37.7 ± 0.6
37.8 ± 02
37.9 ± 0.1
38.4 ± 0.5
38.5 ± 0.4
Note: there was a significant difference in MABP between the two groups immediately after ROSC, , no significant difference among the other parameters.
