Research Article

The Effect of Prophylactic Anticoagulation with Heparin on the Brain Cells of Sprague-Dawley Rats in a Cardiopulmonary-Cerebral Resuscitation Model

Table 3

The comparison of the CPR success and 72 h survival rates of nonanticoagulation and heparin groups.

Time from asphyxiation to CA (s)Time from CPR to ROSC (s)Time of tracheal extubation (h)CPR success rate (%)72 h survival rate (%)

Nonanticoagulation167 ± 2081.3 ± 20.46.9 ± 1.464 (16/25)62.6 (10/16)
Heparin196 ± 3242.7 ± 15.84.8 ± 1.292 (23/25)91.3 (21/23)

Note: the measurement data are expressed as mean ± SD, while the count data is expressed as percentages. There is significant difference in the time from asphyxiation to CA and from CPR to ROSC between groups of nonanticoagulation and heparin, ; the CPR success rate and survival rate 72 hours after ROSC between the two groups were also significantly different, .