The Effect of Prophylactic Anticoagulation with Heparin on the Brain Cells of Sprague-Dawley Rats in a Cardiopulmonary-Cerebral Resuscitation Model

Table 4

The ND scores of groups III and IV at different time points after CPR (mean ± SD%).

Groups	Before anesthesia	2 h after ROSC	24 h after ROSC	48 h after ROSC	72 h after ROSC
Control	0 ± 0	—	—	—	0 ± 0
Sham	0 ± 0	—	—	—	0 ± 0
Nonanticoagulation	0 ± 0	62.9 ± 8.2	39.2 ± 8.3	28.2 ± 5.3	24 ± 7.1
Heparin	0 ± 0	49.1 ± 9.7	18.1 ± 6.7	4.9 ± 3.9	4.5 ± 2.1

Note: before anesthesia, the ND score of all the groups was 0 + 0%; there was a significant difference in ND scores between groups of nonanticoagulation and heparin at 2 h, 24 h, 48 h, and 72 h after CPR, .