The Effect of Prophylactic Anticoagulation with Heparin on the Brain Cells of Sprague-Dawley Rats in a Cardiopulmonary-Cerebral Resuscitation Model

Table 5

Ischemic neuron cell count from different brain regions at different time points after ROSC in the 4 groups (mean t SD%).

Group	Hippocampus	Cortex	Thalamus	Cerebellum	Shell caudate nucleus
Control	0 ± 0	0 ± 0	0 ± 0	0 ± 0	0 ± 0
Sham	0 ± 0	0 ± 0	0 ± 0	0 ± 0	0 ± 0
Nonanticoagulation	65.7 ± 13.46	28.3 ± 7.04	30 ± 5.19	18.7 ± 3.33	18.4 ± 5.62
Heparin	26.95 ± 8.42	17.53 ± 6.43	23 ± 4.47	12.74 ± 2.84	12.95 ± 3.73

Note: upon comparing the HD count from the different brain regions, there is a significant difference between the groups of nonanticoagulation and heparin, .