RNA-Seq Analysis of the Liver Transcriptome Reveals the Networks Regulating Treatment of Sitagliptin Phosphate plus Fuzhujiangtang Granule in the Zucker Diabetic Fatty Rats

Table 7

Topological features for top 20 genes in the PPI network.

Name	Degree	Average shortest path length	Betweenness centrality	Closeness centrality	Clustering coefficient	Topological coefficient
Lrrk2	2413	1.9294	0.3861	0.5183	0.0022	0.0026
Irak3	1387	2.1311	0.1271	0.4692	0.0039	0.0032
Txndc11	968	2.2135	0.1126	0.4518	0.0046	0.0038
Rfc5	652	2.6483	0.0679	0.3776	0.0022	0.0066
Dusp1	848	2.3084	0.0644	0.4332	0.0066	0.0044
Afp	393	2.7355	0.0565	0.3656	0.0023	0.0069
Tfrc	416	2.6417	0.0563	0.3785	0.0027	0.0066
Dnajb9	592	2.3182	0.0549	0.4314	0.0062	0.0044
Psmb8	443	2.7090	0.0510	0.3691	0.0024	0.0077
Oas1a	452	2.1887	0.0461	0.4569	0.0067	0.0077
Dusp10	651	2.3613	0.0320	0.4235	0.0089	0.0051
Cox18	398	2.6361	0.0315	0.3793	0.0047	0.0064
Bicc1	267	2.8185	0.0308	0.3548	0.0015	0.0113
Tomm40 l	321	2.7891	0.0288	0.3585	0.0031	0.0096
RT1-S3	217	2.7531	0.0259	0.3632	0.0052	0.0093
Mrps18b	231	2.9355	0.0258	0.3407	0.0011	0.0137
Mtx2	195	2.9554	0.0256	0.3384	0.0024	0.0123
Rpa1	316	2.7432	0.0254	0.3645	0.0053	0.0081
Ddo	215	2.8658	0.0249	0.3489	0.0020	0.0120
Sult1b1	136	2.9094	0.0238	0.3437	0.0021	0.0110