Cardioprotective Effect of Croton macrostachyus Stem Bark Extract and Solvent Fractions on Cyclophosphamide-Induced Cardiotoxicity in Rats

Figure 6

Histopathological changes in the heart tissue treated with ethyl acetate fraction. (a) Normal control group (normal structures of the heart). (b) Cyclophosphamide control group (necrosis and hemorrhage). (c) Enalapril control group (mild congestion and necrosis). (d) Ethyl acetate fraction at 100 mg/kg (nearly normal structure, edema). (e) Ethyl acetate fraction at 200 mg/kg (hemorrhage).

(a)

(b)

(c)

(d)

(e)