The Ethanol Extract of Avocado (Persea americana Mill. (Lauraceae)) Seeds Successfully Induces Implant Regression and Restores Ovarian Dynamic in a Rat Model of Endometriosis

Table 1

Effects of the ethanol extract of P. americana seeds on the variation of endometriotic implant volume and tissue levels of MDA and GSH.

Groups	Variation of implant volume (mm^3)	MDA (nM/mg)	GSH (nM/min/mg)
[ENDO + DW]	104.706 ± 15.24	5.102 ± 0.334	154.558 ± 13.529
[ENDO + LTZ]	24.005 ± 16.23	9.192 ± 0.551	305 ± 9.644
[ENDO + EE 12.5]	20.146 ± 11.22	9.307 ± 0.730	300.294 ± 14.670
[ENDO + EE 25]	(−) 24.907 ± 23.33	10.243 ± 0.408	344.411 ± 13.295
[ENDO + EE 50]	(−) 69.156 ± 13.82	5.256 + 0.393	233.529 ± 10.051

Results are expressed as mean ± SEM, n = 5, , , and versus [ENDO + DW]. ENDO: animals with endometriosis; DW: distilled water; LTZ: letrozole; EE: ethanol extract of P. americana seeds. MDA: malondialdehyde; GSH: glutathione.