Chinese Herbal Medicines and Conventional Chronic Heart Failure Treatment for the Management of Chronic Heart Failure Complicated with Depression: A Systematic Review and Meta-Analysis
Table 1
Baseline characteristics of included studies.
Author
N
Gender
Age (years)
NYHA
Intervention
Duration (weeks)
Adverse reaction
Outcome
T
C
M
F
T
C
Class
T
C
Gong et al. 2017
33
33
41
25
66.5 ± 7.8
66.8 ± 7.2
II∼III
Sini powder + CMT
CMT
12
No
Effective rate of cardiac function/HAMD-24
Li et al. 2009
22
22
23
21
55.1 ± 6.8
54.6 ± 6.6
II∼III
Xiaoyao powder + CMT
CMT
16
No
HAMD-17/LVEF
Hua et al. 2011
78
77
89
66
62.7 ± 4.6
III∼V
Shugan jieyu capsule + CMT
CMT
8
Yes
HAMD-24/LVEF
Yao et al. 2010
20
20
29
11
58.9 ± 6.83
56.4 ± 6.71
II∼III
Xinshu granules + CMT
CMT
8
NR
HAMD-17
Qi et al. 2013
30
30
34
26
72.23 ± 6.56
73.07 ± 6.52
II∼IV
Yixin decoction + CMT
CMT
4
NR
HAMD-21/MLHFQ
Wang et al. 2017
30
30
34
26
68.50 ± 3.03
69.27 ± 3.29
II∼IV
Kaixin powder + CMT
CMT
4
No
Effective rate of cardiac function/MLHFQ
Zhang et al. 2013
43
40
55
28
59.31 ± 10.19
61.0 ± 8.39
II∼IV
Qili qiangxin capsules + CMT
CMT
12
No
Effective rate of cardiac function/LVEF/HAMD-17
Xue et al. 2016
69
68
75
62
61.9 ± 10.8
62.6 ± 11.3
II∼III
Zhenwu decoction with xiaoyao powder + CMT
CMT
12
No
Effective rate of cardiac function/HAMD-24/LVEF/MLHFQ
Wang et al. 2016
39
42
28
53
61.32 ± 15.34
62.31 ± 14.09
II∼IV
Shuxin soup + CMT
CMT
12
NR
Effective rate of cardiac function/HAMD-24/LVEF
Su et al. 2006
62
61
80
43
61.3 ± 15.34
62.31 ± 14.09
II∼III
Wuling powder + CMT
CMT
8
NR
HAMD-17/LVEF
Gu et al. 2017
30
30
27
33
72.6 ± 6.1
72.3 ± 5.6
I∼III
Yixin jieyu decoction + CMT
CMT
8
No
Effective rate of cardiac function/HAMD-17
Wang et al. 2015
26
26
31
21
63.18 ± 12.46
62.35 ± 11.65
II∼III
Shuganjieyu capsules + CMT
CMT
24
Yes
HAMD-17/MLHFQ/LVEF
Liao et al. 2011
31
30
25
36
64.2 ± 12.5
≥II
Shuganjieyu capsules + CMT
CMT
4
NR
HAMD-17/LVEF
CMT: Conventional medicine treatment; NR: no report; HAMD: Hamilton depression rating scale; LVEF: left ventricular ejection fraction; MLHFQ: The Minnesota Living with Heart Failure Questionnaire.
