Chinese Herbal Medicines and Conventional Chronic Heart Failure Treatment for the Management of Chronic Heart Failure Complicated with Depression: A Systematic Review and Meta-Analysis

Table 2

Subgroup analysis for treatment duration and mean age.

Depression outcome total or subgroup	Trials	Effects model	Pooled effect	95% CI	value	I^2 (%)
Total	12	Random	SMD−1.31	−1.68, −0.95	<0.001	81.1
Total (remove Gong et al.)	11	Random	SMD−1.12	−1.37, −0.87	<0.001	61.3
Mean age
<65 years	3	Random	SMD−1.01	1.20, −0.81	<0.001	29.7
>65 years	9	Random	SMD−2.86	−4.63, −1.08	0.02	91.9
Treatment duration
<8 weeks	3	Random	SMD−0.93	−1.33, −0.53	<0.001	24.1
8–12 weeks	7	Random	SMD−1.57	−2.14, −1.00	<0.001	88.7
>12 weeks	2	Random	SMD−1.19	−1.66, −0.72	<0.001	0