Increment of Lysosomal Biogenesis by Combined Extracts of Gum Arabic, Parsley, and Corn Silk: A Reparative Mechanism in Mice Renal Cells

Table 2

The scores (in Kcal/mol) of top-scoring 11 compounds identified from parsley and corn silk as docked in the active sites of GPR43 (FFAR2) and GPR41 (FFAR3) homology models.

Ligand	FFAR2	FFAR3
Staphinine; demethoxy	−7.61	−8.93
Campesterol	−7.57	−9.46
Ergosta-7,22-dien-3beta-ol, acetate	−6.84	−10.27
Epicatechin-3-O-gallate	−6.58	−6.72
Imperatorin	−6.40	−9.03
13-Hydroxy-10-oxo-11-octadecenoic acid; (±)-(E)-form, lactone	−6.20	−8.41
Lythranidine	−6.14	−7.76
2″-O-α-L-rhamnosyl-6-C-quinovosyl-luteolin	−5.99	−6.36
7,4′-Dihydroxy-3,5-dimethoxyflavone	−5.69	−6.99
L-Arabinoside	−5.69	−8.41
Chrysoeriol	−5.44	−7.24

Top-scoring 3 compounds for FFAR3. The scores are sorted according to FFAR2.