Efficacy and Safety of Tongning Gel for Knee Osteoarthritis: A Multicentre, Randomized, Double-Blinded, Parallel, Placebo-Controlled, Clinical Trial

Table 4

Comparison of adverse events and incidence of adverse reactions between two groups.

	TNG (n = 431)		PC (n = 144)		value
	Frequency	Case (％)	Frequency	Case (％)
Adverse event	25	16 (3.71)	17	13 (9.03)
Adverse reaction	2	2 (0.46)	6	4 (2.78)
Significant adverse event	2	2 (0.46)	0	0 (0.00)
Serious adverse event	1	1 (0.23)	1	1 (0.69)

Comparison between TNG group and PC group by Fisher’s exact test.