Antileukemic Effect of Palladium Nanoparticles Mediated by White Tea (Camellia sinensis) Extract In Vitro and in WEHI-3B-Induced Leukemia In Vivo

Table 1

Serum liver and renal function parameters of healthy (negative) control mice or with induced leukemia after 28 days of treatment as stated.

Animal group	ALP (U/L)	ALT (U/L)	AST (U/L)	Urea (mmol/L)	Creatinine (μmol/L)
Negative control	110.3 ± 2.1	60.9 ± 1.2	142.1.2 ± 1.3	7.85 ± 0.6	31.65 ± 0.8
Induced leukemia control	200.1 ± 1.1	155.55 ± 1.5	205.0.6 ± 0.9	12.55 ± 0.5	50.7 ± 2.3
Blank-NPs	195.01 ± 1.4	149.2 ± 1.1	197.5 ± 1.6	11.95 ± 0.55	51.6 ± 1.3
50 mg/kg [email protected]	151.0 ± 0.6^Ψ	100.3 ± 1.7^Ψ	175.1.8 ± 0.8^Ψ	9.05 ± 0.65^Ψ	39.4 ± 0.4^Ψ
100 mg/kg [email protected]	128.4 ± 0.11^Ψ	75.95 ± 1.45^Ψ	155.1 ± 2.2^Ψ	8.6.45 ± 0.25^Ψ	35.23 ± 0.7^Ψ
5 mg/kg ATRA	112.3 ± 1.5^Ψ	62.0 ± 1.0^Ψ	146.2 ± 0.35^Ψ	8.1 ± 0.5^Ψ	32 ± 0.9^Ψ

compared with negative control, compared with induced leukemia control by one-way ANOVA followed by Tukey’s B-test. ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase. Values are mean ± SD (n = 6).