Evidence-Based Complementary and Alternative Medicine / 2020 / Article / Tab 3

Research Article

Antileukemic Effect of Palladium Nanoparticles Mediated by White Tea (Camellia sinensis) Extract In Vitro and in WEHI-3B-Induced Leukemia In Vivo

Table 3

Histopathological scoring of spleen in mice with induced leukemia, or in healthy (negative) control animals, after 28 days of treatment as stated.

Animal groupLeukemic cells %Nonleukemic cells %ScoreIndication

Negative control0.0 ± 0.0100.0 ± 0.00Normal
Induced leukemia control85.51 ± 1.4a14.49 ± 0.74Severe change
50 mg/kg Pd@W.tea-NPs19.65 ± 0.45b80.35 ± 0.551Mild change
100 mg/kg Pd@W.tea-NPs18.2 ± 0.25b81.8 ± 0.151Mild change
Blank-NPs72.25 ± 2.1a27.75 ± 1.54Severe change
5 mg/kg ATRA13.50 ± 0.16b86.50 ± 0.261Mild change

Values are mean ± SD, n = 4 sections. a - compared with negative control; b– compared with induced leukemia control by one-way ANOVA followed by Tukey’s B-test. Sections were stained with H&E.

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