Research Article

Exploring the Molecular Mechanism of Qing Guang An Granule in Treating Glaucoma Using Network Pharmacology and Molecular Docking

Table 1

The active compounds from the eight medicine herbs.

CodeMolecule nameOB%DLHerb name

M1Mairin55.380.78HQ
M2Jaranol50.830.29HQ
M3Hederagenin36.910.75HQ/FL
M4(3S, 8S, 9S, 10R, 13R, 14S, 17R)-10,13-dimethyl-17-[(2R, 5S)-5-propan-2-yloctan-2-yl]-2, 3, 4, 7, 8, 9, 11, 12, 14, 15, 16, 17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol36.230.78HQ/BZ
M5Isorhamnetin49.600.31HQ
M63,9-di-O-methylnissolin53.740.48HQ
M77-O-methylisomucronulatol74.690.30HQ
M89,10-Dimethoxypterocarpan-3-O-β-D-glucoside36.740.92HQ
M9(6aR,11aR)-9,10-dimethoxy-6a,11a-dihydro-6H-benzofurano [3,2-c]chromen-3-ol64.260.42HQ/DL
M10Bifendate31.100.67HQ
M11Formononetin69.670.21HQ
M12Calycosin47.750.24HQ
M13Kaempferol41.880.24HQ/HH/SDH
M14FA68.960.71HQ
M15Isomucronulatol-7, 2′-di-O-glucosiole49.280.62HQ
M161, 7-Dihydroxy-3, 9-dimethoxy pterocarpene39.050.48HQ
M17Quercetin46.430.28HQ/CQZ/HH/SDH
M18Dinatin30.970.27CQZ
M19Sitosterol36.910.75CQZ/CS
M20Daucostero_qt36.910.75CQZ
M21Dihydrotricetin58.120.28CQZ
M22Hypolaetin33.240.28CQZ
M23orobanchoside_qt55.990.82CQZ
M24Poriferast-5-en-3beta-ol36.910.75HH
M254-[(E)-4-(3, 5-dimethoxy-4-oxo-1-cyclohexa-2, 5-dienylidene)but-2-enylidene]-2, 6-dimethoxycyclohexa-2, 5-dien-1-one48.470.36HH
M26Lignan43.320.65HH
M27Pyrethrin II48.360.35HH
M286-Hydroxykaempferol62.130.27HH
M29Baicalein33.520.21HH/CS
M30qt_carthamone51.030.20HH
M31Quercetagetin45.010.31HH
M327, 8-Dimethyl-1H-pyrimido[5,6-g]quinoxaline-2, 4-dione45.750.19HH
M33Beta-carotene37.180.58HH
M34Baicalin40.120.75HH/CS
M35Beta-sitosterol36.910.75HH/CS
M36Stigmasterol43.830.76HH/CS
M37Luteolin36.160.25HH/SDH
M38CLR37.870.68HH
M39(2R)-2-[(3S, 5R, 10S, 13R, 14R, 16R, 17R)-3,16-dihydroxy-4, 4, 10, 13, 14-pentamethyl-2, 3, 5, 6, 12, 15, 16, 17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-enoic acid30.930.81FL
M40Trametenolic acid38.710.80FL
M41Cerevisterol37.960.77FL
M42Ergosta-7, 22E-dien-3beta-ol43.510.72FL
M43Ergosterol peroxide40.360.81FL
M44Ellagic acid43.060.43CS
M45Paeoniflorgenone87.590.37CS
M46Paeoniflorin53.870.79CS
M47Spinasterol42.980.76CS
M48(+)-catechin54.830.24CS
M49(2R,3R)-4-methoxyl-distylin59.980.30CS
M50Stigmast-7-en-3-ol37.420.75CS/DL
M51Ethyl oleate (NF)32.400.19CS
M52Campest-5-en-3beta-ol37.580.71CS
M5314-Acetyl-12-senecioyl-2E,8Z,10E-atractylentriol63.370.30BZ
M543β-acetoxyatractylone54.070.22BZ
M558β-ethoxy atractylenolide III35.950.21BZ