Research Article
Exploring the Molecular Mechanism of Qing Guang An Granule in Treating Glaucoma Using Network Pharmacology and Molecular Docking
Table 2
The GO enrichment analysis.
| Category | Description | Cout | Pop hits | value | Fold enrichment |
| BP | Response to toxic substance | 5 | 85 | 2.2E − 6 | 49.39 | Response to gamma radiation | 3 | 31 | 5.5E − 4 | 81.25 | Positive regulation of intrinsic apoptotic signaling pathway | 3 | 33 | 6.3E − 4 | 76.33 | Negative regulation of the apoptotic process | 5 | 455 | 1.5E − 3 | 9.23 | Apoptotic process | 5 | 567 | 3.3E − 3 | 7.40 | Cellular response to hypoxia | 3 | 96 | 5.2E − 3 | 26.24 | Negative regulation of cell growth | 4 | 121 | 3.3E − 4 | 27.76 | Cellular response to DNA damage stimulus | 3 | 208 | 2.3E − 2 | 12.11 | Ovarian follicle development | 3 | 42 | 1.0E − 3 | 59.97 |
| CC | Mitochondrion | 6 | 1331 | 1.0E − 2 | 4.11 | Mitochondrial outer membrane | 3 | 149 | 1.0E − 2 | 18.35 | Endoplasmic reticulum membrane | 4 | 862 | 5.8E − 2 | 4.23 | Endoplasmic reticulum | 3 | 828 | 2.1E − 1 | 3.30 | Membrane | 3 | 2200 | 6.9E − 1 | 1.24 |
| MF | Identical protein binding | 5 | 749 | 8.7E − 3 | 5.63 | Protein heterodimerization activity | 4 | 465 | 1.4E − 2 | 7.26 | Ubiquitin protein ligase binding | 3 | 287 | 4.1E − 2 | 8.82 | Protein homodimerization activity | 5 | 730 | 8.0E − 3 | 5.78 |
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