Research Article

Evaluation of Immunomodulatory and Antiarthritic Potential of Trigonella gharuensis Extracts

Table 3

T. gharuensis extracts significantly reduced paw edema in arthritic rats.

DaysVehicle controlArthritic control (ml)Piroxicam (ml)EETG (ml)NHTG (ml)

Day 80.000 ± 0.0000.938 ± 0.0120.953 ± 0.0120.937 ± 0.0080.932 ± 0.014
Day 150.000 ± 0.0001.138 ± 0.0150.773 ± 0.0070.770 ± 0.0130.863 ± 0.006
Day 220.000 ± 0.0001.232 ± 0.0100.699 ± 0.0060.737 ± 0.0090.727 ± 0.010
Day 280.000 ± 0.0001.372 ± 0.0080.622 ± 0.0070.630 ± 0.0070.670 ± 0.017

Value of normal paw is considered as zero. EETG, ethanolic extract of T. gharuensis; NHTG, n-hexane extract of T. gharuensis (400 mg/kg); piroxicam (10 mg/kg). Values were denoted as mean ± SEM. when compared with the arthritic control group.