Evaluation of Immunomodulatory and Antiarthritic Potential of Trigonella gharuensis Extracts

Table 4

T. gharuensis attenuated histopathological parameters.

Parameters	Vehicle control	Arthritic control	Piroxicam	EETG	NHTG
Infiltration of inflammatory cells	0.000 ± 0.000	2.573 ± 0.073	1.566 ± 0.073	1.917 ± 0.154	2.083 ± 0.083
Pannus formation	0.000 ± 0.000	3.405 ± 0.073	2.522 ± 0.103	2.583 ± 0.083	2.583 ± 0.083
Bone erosion	0.000 ± 0.000	2.543 ± 0.073	2.073 ± 0.073	2.083 ± 0.083	2.167 ± 0.105

Value of normal paw is considered as zero. EETG, ethanolic extract of T. gharuensis (400 mg/kg); NHTG, n-hexane extract of T. gharuensis (400 mg/kg); piroxicam (10 mg/kg). Values were denoted as mean ± SEM. and when compared with the arthritic control group.