Research Article
The Role of Oxymatrine in Amelioration of Acute Lung Injury Subjected to Myocardial I/R by Inhibiting Endoplasmic Reticulum Stress in Diabetic Rats
Figure 5
OMT inhibits ERS-induced apoptosis in diabetic rats. (a) Expression of caspase-3, caspase-9, caspase-12, Bax, and Bcl-2 was determined using Western blot analysis. (b), (c), (d), and (e) Quantification of Western blot results. (f) TUNNEL staining in lung tissues. Values are expressed as the mean ± SD from three independent experiments, n = 3. and vs. the Sham group; vs. the I/R group; , vs. the DM + I/R group. OMT, oxymatrine; ERS, endoplasmic reticulum stress; I/R, ischemia/reperfusion; DM, diabetes mellitus.
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