An Apriori Algorithm-Based Association Rule Analysis to Identify Herb Combinations for Treating Uremic Pruritus Using Chinese Herbal Bath Therapy

Table 1

Summary of 17 RCTs included in the meta-analysis on CHBT treatment for UP.

Study (year)	Study design	Inclusion criteria	Herbs	Overall bias
Du, 2009 [23]	RCT	HD	Tufulin, chuanxiong, baizhi, baixianpi, difuzi, kushen, jingjie, xixin, danggui, chantui	High
Du et al., 2004 [24]	RCT	HD	Tufulin, chuanxiong, baixianpi, difuzi, heshouwu, kushen, jingjie, xixin, danggui	High
Gao and Ye, 2012 [25]	RCT	HD	Tufulin, dahuang, baixianpi, difuzi, heshouwu, fangfeng, taoren, mahuang, danshen, jixueteng	High
Guo et al., 2009 [26]	RCT	HD	Dahuang, chuanxiong, danshen, baixianpi, difuzi, honghua, kushen, xixin, mahuang, danggui	High
Jia et al., 2012 [27]	RCT	HD	Dahuang, chuanxiong, baizhi, baixianpi, difuzi, zaojiaoci, kushen, xixin, danggui, chantui, jixueteng	High
Jia, Li and Fei, 2012 [28]	RCT	HD	Dahuang, chuanxiong, baizhi, baixianpi, difuzi, zaojiaoci, kushen, xixin, danggui, chantui, jixueteng	High
Lan, 2017 [29]	RCT	HD	Dahuang, chuanxiong, danshen, baixianpi, difuzi, honghua, kushen, xixin, mahuang, danggui	High
Lin, 2014 [30]	RCT	HD	Dahuang, chuanxiong, baizhi, baixianpi, difuzi, zaojiaoci, kushen, xixin, danggui, chantui, jixueteng	High
Shen, 2014 [31]	RCT	HD	Tufulin, danshen, baixianpi, quanxie, difuzi, heshouwu, kushen, xixin, shechuangzi, mahuang, danggui, wugong, chantui, biejia	High
Wang et al., 2013 [32]	RCT	HD	Dahuang, chuanxiong, baixianpi, difuzi, chishao, kushen, xixin, shechuangzi, juhua, danggui, chantui	High
Wen, 2007 [33]	RCT	HD	Tufulin, chuanxiong, baijili, difuzi, wushaoshe, jingjie, xixin, danggui, jixueteng	High
Yao, 2015 [34]	RCT	HD	Tufulin, baixianpi, difuzi, kushen, jingjie, chantui	High
Yu et al., 2017 [35]	RCT	HD	Tufulin, chuanxiong, baixianpi, difuzi, kushen, jingjie, zisuye, danggui, jixuecao, chantui	High
Zhang et al., 2014 [36]	RCT	HD	Tufulin, difuzi, baixianpi, kushen, chantui, jingjie	High
Zhang et al., 2012 [37]	RCT	HD	Baizhi, baijili, fangfeng, songjie, qianghuo, guizhi, jingjie, xixin, shechuangzi, mahuang, cangzhu, tanxiang, chantui	High
Zhao, 2011 [38]	RCT	HD	Wujiapi, baizhi, baijili, shenjincao, fangfeng, peilan, songjie, qianghuo, weilingxian, guizhi, taozhi, haitongpi, jingjie, xixin, shechuangzi, mahuang, zisuye, huaizhi, cangzhu, tanxiang, chantui, huoxiang	Some
Zheng, 2016 [39]	RCT	HD	Chuanxiong, shengdihuang, difuzi, chishao, fangfeng, kushen, mahuang, danggui, chantui	High

RCT = randomized controlled trial; CHBT = Chinese herbal bath therapy; UP = uremic pruritus; HD = hemodialysis.