|
Essential oil | Species | Cell types | Inflammation of the species | Tested indicators | Assays biochemical | Molecular | Conclusion | Reference |
|
Maqian fruits essential oil | Rutaceous | THP-1 cell line | LPS-induced | TNF-α, IL-1β, IKK, IκB | ELISA | Western blot | This essential oil inhibits inflammation by lowering levels of inflammatory factors (TNF-α and IL-1β) and preventing phosphorylation of IKK and IκB | [16] |
Essential oil from waste leaves of Curcuma longa L. | Zingiberaceae | Human keratinocyte cell line (HaCaT) | LPS and TPA-induced | TNF-α, IL-6, IL-1β | — | RT-PCR | Under the premise of no toxicity, this essential oil can inhibit the level of inflammatory factors (TNF-α, IL-6, IL-1β) and further inhibit the inflammatory response | [17] |
Essential oil from Fructus Alpinia zerumbet | Zingiberaceae | Human aortic endothelial cells | LPS-induced | ICAM-1, VCAM-1 | - | PCR, western blot | This essential oil prevented LPS-induced HAEC activation and inflammation. | [18] |
Essential oil from zanthoxylum coreanum nakai | Rutaceae | RAW264.7 cells | LPS-induced | TNF-α, IL-6, | ELISA | — | This essential oil inhibits inflammation by regulating the NF-κB and MAPKs signalling pathways | [19] |
Essential oil from acorus gramineusand and euodia ruticarpa | Acorus and tetradium | Mouse primary splenocytes and peritoneal macrophages | LPS-induced | Th1, IL-2, Th2 IL-5, TNF-α, IL-10 | ELISA | — | These two essential oils have the potential to regulate Th1/Th2 balance of spleen cells and suppress macrophage inflammation | [20] |
Essential oils from gynura procumbens | Compositae | RAW264.7 cells | LPS-induced | COX-2 | ELISA | — | This essential oil can suppress nociceptive inflammation by regulating COX-2 levels | [21] |
Essential oil from artemisia argyi | Artemisia | RAW264.7 cells | LPS-induced | NO, PGE2, ROS, TNF-α, IL-6, IFN-β and MCP-1 | — | PCR, western blot | This essential oil inhibits inflammation through down-regulation of the JAK/STATs signalling | [22] |
Essential oil from atractylodes macrocephala | Compositae | ANA-1 cells. | LPS-induced | NO | — | — | This essential oil reduces NO levels after stimulation and suppresses inflammation | [23] |
Essential oil from citrus limetta; | Citrus L. | RAW264.7 cells | LPS-induced | TNF-α, IL-6, IL-1β | ELISA | — | This essential oil can inhibit inflammation by inhibiting the expression of a variety of cytokines | [24] |
Essential oil from citrus aurantium L. var. amara | Citrus aurantium L. var. amara engl | RAW264.7 cells | LPS-induced | iNOS, IL-6, TNF-α, IL-1β COX-2. | — | Western blot RT-PCR | This essential oil inhibits inflammation by regulating the NF-κB and MAPKs signalling pathway | [25] |
|